General Information:

Id: 58 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type I - [OMIM]
Rattus norvegicus
BTO:0001185 RINm5F cell
article
Reference: Song MY et al.(2009) Sulforaphane protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathway. Toxicol. Appl. Pharmacol. 235: 57-67 [PMID: 19071154]

Interaction Information:

Comment H(2)O(2) production was abolished when RIN cells were either pretreated with SFN or transfected with Nrf2 before incubation with cytokines.
Formal Description
Interaction-ID: 190

gene/protein

NFE2L2

decreases_quantity of

drug/chemical compound

H2O2

if Nrf2 is overexpressed in cytokine treated cells