General Information:

Id: 5,879 (click here to show other Interactions for entry)
Diseases: Lung disease
Pulmonary hypertension
Homo sapiens
Bmpr2(del)Ex2/+, 8-10 week-old
lung
article
Reference: Frank DB et al.(2008) Increased susceptibility to hypoxic pulmonary hypertension in Bmpr2 mutant mice is associated with endothelial dysfunction in the pulmonary vasculature Am. J. Physiol. Lung Cell Mol. Physiol. 294: L98-L109 [PMID: 18024717]

Interaction Information:

Comment Pulmonary eNOS was upregulated by hypoxia in wild-type mice, but this response was abrogated in Bmpr2(del)Ex2/+ mutants. This was associated with a corresponding increase in iNOS expression in hypoxic Bmpr2(del)Ex2/+ mutant lungs.
Formal Description
Interaction-ID: 55606

increases_quantity of

gene/protein

NOS3

Drugbank entries Show/Hide entries for NOS3