General Information:

Id: 5,879 (click here to show other Interactions for entry)
Diseases: Lung disease
Pulmonary hypertension
Homo sapiens
Bmpr2(del)Ex2/+, 8-10 week-old
lung
article
Reference: Frank DB et al.(2008) Increased susceptibility to hypoxic pulmonary hypertension in Bmpr2 mutant mice is associated with endothelial dysfunction in the pulmonary vasculature Am. J. Physiol. Lung Cell Mol. Physiol. 294: L98-L109 [PMID: 18024717]

Interaction Information:

Comment eNOS expression is regulated by hypoxia-induced BMP signaling in pulmonary endothelial cells. This response is defective in pulmonary endothelial cells from Bmpr2(del)Ex2/+ mutant mice.
Formal Description
Interaction-ID: 55554

increases_activity of

gene/protein

BMPR2