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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	5,868 (click here to show other Interactions for entry)
Diseases:	Diabetes mellitus, type II - [OMIM] Insulin resistance
Organism:	Mammalia
Publication type:	review
Reference:	Teperino R et al.(2014) Canonical and non-canonical Hedgehog signalling and the control of metabolism Semin. Cell Dev. Biol. 33: 81-92 [PMID: 24862854]

Interaction Information:

Comment	Hedgehog signalling controls development of both endocrine and exocrine pancreas, as well as their function in adults. Furthermore, inappropriate activation of the pathway, alone or in combination with other oncogenes is associated with the development of pancreatic adenocarcinoma (PDAC).
Formal Description Interaction-ID: 55491	process smoothened signaling pathway affects_activity of tissue/cell line endocrine pancreas

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