General Information:

Id: 574 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mammalia
review
Reference: Zhou S et al.(2007) Regulation of gamma-secretase activity in Alzheimers disease. Biochemistry 46: 2553-2563 [PMID: 17298085]

Interaction Information:

Comment Site-directed mutagenesis indicated that PS1 residues Ser353, Ser357, and Ser397 are GSK3B targets.
Formal Description
Interaction-ID: 3049

gene/protein

GSK3B

affects_activity of

gene/protein

PSEN1

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