General Information:

Id: 5,742 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
MODY, type IV - [OMIM]
Homo sapiens
Reference: Clocquet AR et al.(2000) Impaired insulin secretion and increased insulin sensitivity in familial maturity-onset diabetes of the young 4 (insulin promoter factor 1 gene) Diabetes 49: 1856-1864 [PMID: 11078452]

Interaction Information:

Comment An improved peripheral tissue sensitivity probably compensates at least in part for the diminished insulin secretion.
Formal Description
Interaction-ID: 54385

decreases_activity of

in pancreas, in pancreatic beta cells