General Information:

Id: 559 (click here to show other Interactions for entry)
Diseases: Cancer
Diabetes mellitus, type II - [OMIM]
Insulin resistance
Peutz-Jeghers syndrome - [OMIM]
Mammalia
article
Reference: Shaw RJ et al.(2004) The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. Proc. Natl. Acad. Sci. U.S.A. 101: 3329-3335 [PMID: 14985505]

Interaction Information:

Comment The kinase activity of LKB1 immunoprecipitated from cells treated with peroxide or AICAR was not increased compared with that from untreated control cells, as measured both by autophosphotylation and transphpsphorylation or the MBP-AMPK fusion.
Formal Description
Interaction-ID: 2975

drug/chemical compound

H2O2

NOT increases_activity of

gene/protein

STK11