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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	551 (click here to show other Interactions for entry)
Diseases:	Breast cancer - [OMIM] Diabetes mellitus, type II - [OMIM] Insulin resistance Obesity - [OMIM]
Organism:	Homo sapiens
Gender:	female
Tissue/Cell line:	primary human breast adipose stromal cells
Publication type:	article
Reference:	Brown KA et al.(2009) Subcellular localization of cyclic AMP-responsive element binding protein-regulated transcription coactivator 2 provides a link between obesity and breast cancer in postmenopausal women Cancer Res. 69: 5392-5399 [PMID: 19509226]

Interaction Information:

Comment	Leptin induces aromatase expression via CRTC2 translocation to the nucleus and inhibition of LKB1 expression in human adipose stromal cells.
Formal Description Interaction-ID: 2884	gene/protein LEP decreases_expression of gene/protein STK11 in adipose stromal cells

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