General Information:
Id: | 551 (click here to show other Interactions for entry) |
Diseases: |
Breast cancer
- [OMIM]
Diabetes mellitus, type II - [OMIM] Insulin resistance Obesity - [OMIM] |
Homo sapiens | |
female | |
primary human breast adipose stromal cells | |
article | |
Reference: | Brown KA et al.(2009) Subcellular localization of cyclic AMP-responsive element binding protein-regulated transcription coactivator 2 provides a link between obesity and breast cancer in postmenopausal women Cancer Res. 69: 5392-5399 [PMID: 19509226] |
Interaction Information:
Comment | Leptin induces aromatase expression via CRTC2 translocation to the nucleus and inhibition of LKB1 expression in human adipose stromal cells. |
Formal Description Interaction-ID: 2883 |
|
Drugbank entries | Show/Hide entries for CYP19A1 |
Comment | Leptin induces aromatase expression via CRTC2 translocation to the nucleus and inhibition of LKB1 expression in human adipose stromal cells. |
Formal Description Interaction-ID: 2884 |
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Comment | Leptin induces aromatase expression via CRTC2 translocation to the nucleus and inhibition of LKB1 expression in human adipose stromal cells. |
Formal Description Interaction-ID: 2888 |
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