General Information:

Id: 549 (click here to show other Interactions for entry)
Diseases: Breast cancer - [OMIM]
Colorectal cancer - [OMIM]
Diabetes mellitus, type II - [OMIM]
Insulin resistance
Metabolic syndrome
Obesity - [OMIM]
Mammalia
review
Reference: Brown KA and Simpson ER(2010) Obesity and breast cancer: progress to understanding the relationship Cancer Res. 70: 4-7 [PMID: 20028864]

Interaction Information:

Comment Leptin synthesis and plasma levels increase with obesity and higher leptin levels are significantly associated with an increase in breast cancer.
Formal Description
Interaction-ID: 2832

disease

Obesity

increases_quantity of

gene/protein

LEP

in blood