General Information:

Id: 549 (click here to show other Interactions for entry)
Diseases: Breast cancer - [OMIM]
Colorectal cancer - [OMIM]
Diabetes mellitus, type II - [OMIM]
Insulin resistance
Metabolic syndrome
Obesity - [OMIM]
Mammalia
review
Reference: Brown KA and Simpson ER(2010) Obesity and breast cancer: progress to understanding the relationship Cancer Res. 70: 4-7 [PMID: 20028864]

Interaction Information:

Comment AMPK is a master regulator of energy homeostasis, it stimulates pathways of energy production (e.g. glycolysis and fatty acid beta-oxidation) and inhibits those of energy use (e.g. gluconeogenesis and fatty acid and cholesterol biosynthesis).
Formal Description
Interaction-ID: 2829

complex/PPI

AMPK

decreases_activity of

process

gluconeogenesis