General Information:

Id: 5,427 (click here to show other Interactions for entry)
Diseases: Metabolic
Homo sapiens
article
Reference: Geng Y et al.(2014) Insulin receptor substrate 1/2 (IRS1/2) regulates Wnt/beta-catenin signaling through blocking autophagic degradation of dishevelled2 J. Biol. Chem. 289 [PMID: 24616100]

Interaction Information:

Comment IRS1/2 positively regulates Wnt/beta-catenin signaling through Dvl2.(Dishevelled 2). IRS1/2 promotes EMT and cell proliferation through stabilizing Dvl2.
Formal Description
Interaction-ID: 52966

gene/protein

IRS2

increases_activity of