Welcome to cider

Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	5,427 (click here to show other Interactions for entry)
Diseases:	Metabolic
Organism:	Homo sapiens
Publication type:	article
Reference:	Geng Y et al.(2014) Insulin receptor substrate 1/2 (IRS1/2) regulates Wnt/beta-catenin signaling through blocking autophagic degradation of dishevelled2 J. Biol. Chem. 289 [PMID: 24616100]

Interaction Information:

Comment	IRS1/2 positively regulates Wnt/beta-catenin signaling through Dvl2.(Dishevelled 2). IRS1/2 promotes EMT and cell proliferation through stabilizing Dvl2.
Formal Description Interaction-ID: 52966	gene/protein IRS2 increases_activity of process canonical Wnt signaling pathway

Home
Contact

The Helmholtz Zentrum München Imprint and Privacy Policy apply.

Disclaimer: IBIS Databases and associated information are protected by copyright. This server and its associated data and services are for academic, non-commercial use only. The Helmholtz Zentrum München has no liability for the use of results, data or information which have been provided through this server. Neither the use for commercial purposes, nor the redistribution of IBIS database files to third parties nor the distribution of parts of files or derivative products to any third parties is permitted. Commercial users shall contact the Helmholtz Zentrum München for a separate users license.