General Information:

Id: 5,425 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Retinopathy, diabetic
Homo sapiens
BTO:0002335 ARPE-19 cell
article
Reference: Liu Q et al.(2013) Nitrosative stress plays an important role in Wnt pathway activation in diabetic retinopathy Antioxid. Redox Signal. 18: 1141-1153 [PMID: 23066786]

Interaction Information:

Comment Uric acid (UA) inhibits the Wnt-signaling pathway activation induced by 4-Hydroxynonenal (HNE.
Formal Description
Interaction-ID: 52988

drug/chemical compound

4-Hydroxynonenal

increases_activity of