General Information:

Id: 5,417 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
Finnish individuals with homo- zygous or heterozygous LRP5 mutations
article
Reference: Saarinen A et al.(2010) Low density lipoprotein receptor-related protein 5 (LRP5) mutations and osteoporosis, impaired glucose metabolism and hypercholesterolaemia Clin. Endocrinol. (Oxf) 72: 481-488 [PMID: 19673927]

Interaction Information:

Comment The subjects with homozygous or heterozygous LRP5 mutations had impaired bone health and an unexpectedly high frequency of impaired glucose metabolism.
Formal Description
Interaction-ID: 52920

gene/protein

LRP5

affects_activity of