General Information:
Id: | 5,412 (click here to show other Interactions for entry) |
Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance Obesity - [OMIM] |
Mus musculus | |
BTO:0001582 ES-D3 cell | |
article | |
Reference: | Qiao LJ et al.(2011) Simvastatin promotes osteogenic differentiation of mouse embryonic stem cells via canonical Wnt/beta-catenin signaling Mol. Cells 32: 437-444 [PMID: 22058016] |
Interaction Information:
Comment | Collectively, these findings suggest that simvastatin enhances the differentiation of embryonic stem cells (ESCs) toward osteogenic lineage through activation of canonical Wnt/beta-catenin signaling. |
Formal Description Interaction-ID: 52842 |
drug/chemical compound increases_activity of process |
Drugbank entries | Show/Hide entries for Simvastatin |
Comment | Collectively, these findings suggest that simvastatin enhances the differentiation of embryonic stem cells (ESCs) toward osteogenic lineage through activation of canonical Wnt/beta-catenin signaling. |
Formal Description Interaction-ID: 52843 |
process increases_activity of process osteogenic differentiation |