General Information:

Id: 539 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
GPAT1-/- mouse
article
Reference: Lewin TM et al.(2008) Mice deficient in mitochondrial glycerol-3-phosphate acyltransferase-1 have diminished myocardial triacylglycerol accumulation during lipogenic diet and altered phospholipid fatty acid composition Biochim. Biophys. Acta 1781: 352-358 [PMID: 18522808]

Interaction Information:

Comment In sucrose-fed male GPAT1-/- mice, plasma TAG and cholesterol were significantly lower than in wild-type mice.
Formal Description
Interaction-ID: 12825

gene/protein

GPAM

affects_quantity of

drug/chemical compound

Cholesterol

in blood; in male GPAT1-/- mice after high-sucrose diet
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Comment In sucrose-fed female GPAT1-/- mice, values for plasma free fatty acid, TAG, and cholesterol did not differ significantly from control or from treated wild-type mice.
Formal Description
Interaction-ID: 12827

gene/protein

GPAM

NOT affects_quantity of

drug/chemical compound

Cholesterol

in blood; in female GPAT1-/- mice after high-sucrose diet
Drugbank entries Show/Hide entries for