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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	5,399 (click here to show other Interactions for entry)
Diseases:	Diabetes mellitus, type II - [OMIM] Insulin resistance Nephropathy, diabetic
Organism:	Rattus norvegicus
Publication type:	article
Reference:	Lin CL et al.(2008) Simvastatin reverses high glucose-induced apoptosis of mesangial cells via modulation of Wnt signaling pathway Am. J. Nephrol. 28: 290-297 [PMID: 18004065]

Interaction Information:

Comment	Simvastatin restores cell survival and alleviates high glucose induced depression of Wnt/beta catenin signaling.
Formal Description Interaction-ID: 52697	environment high glucose medium decreases_activity of process canonical Wnt signaling pathway

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