General Information:
Id: | 5,325 |
Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
Mus musculus | |
BTO:0002284 MIN-6 cell | |
article | |
Reference: | Zhang Y et al.(2010) Fructose-1,6-bisphosphatase regulates glucose-stimulated insulin secretion of mouse pancreatic beta-cells Endocrinology 151: 4688-4695 [PMID: 20719858] |
Interaction Information:
Comment | Down-regulation of FBP1 in MIN6 cells by small interfering RNA could enhance the glucose-stimulated insulin secretion (GSIS), whereas FBP1-overexpressing MIN6 cells exhibited decreased GSIS. |
Formal Description Interaction-ID: 52074 |
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Drugbank entries | Show/Hide entries for FBP1 |