General Information:

Id: 5,324 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
review
Reference: Leto D and Saltiel AR(2012) Regulation of glucose transport by insulin: traffic control of GLUT4 Nat. Rev. Mol. Cell Biol. 13: 383-396 [PMID: 22617471]

Interaction Information:

Comment Following insulin receptor phosphorylation, APS recruits a complex that comprises the proto-oncogene c-CBL and c-CBL-associated protein (CAP).
Formal Description
Interaction-ID: 52063

gene/protein

SH2B2

increases_activity of

complex/PPI

CBL-SORBS1 complex