General Information:

Id: 5,322 (click here to show other Interactions for entry)
Diseases: Spinocerebellar ataxia 1 - [OMIM]
Spinocerebellar ataxia 7 - [OMIM]
Mus musculus
article/cited
Reference: Gatchel JR et al.(2008) The insulin-like growth factor pathway is altered in spinocerebellar ataxia type 1 and type 7 Proc. Natl. Acad. Sci. U.S.A. 105: 1291-1296 [PMID: 18216249]

Interaction Information:

Comment The insulin-like growth factor binding protein 5 (Igfbp5) was down regulated in spinocerebellar ataxia mouse models (Sca1154Q/2Q and Sca7266Q/5Q).
Formal Description
Interaction-ID: 52058

gene/protein mutant

ATXN1-mut

affects_expression of

gene/protein

IGFBP5