General Information:

Id: 5,319 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
article
Reference: Mackenzie RW and Elliott BT(2014) Akt/PKB activation and insulin signaling: a novel insulin signaling pathway in the treatment of type 2 diabetes Diabetes Metab Syndr Obes 7: 55-64 [PMID: 24611020]

Interaction Information:

Comment Upon activation, Akt/PKB phosphorylates AS160, leading to a reduction in Rab-GAP activity, promoting GLUT-4 translocation and glucose uptake.
Formal Description
Interaction-ID: 52050

gene/protein

AKT3

increases_phosphorylation of

gene/protein

TBC1D4