General Information:

Id: 5,296
Diseases: Diabetes mellitus, type II - [OMIM]
Rattus norvegicus
Reference: Stoffel M et al.(1995) Cloning of rat KATP-2 channel and decreased expression in pancreatic islets of male Zucker diabetic fatty rats Biochem. Biophys. Res. Commun. 212: 894-899 [PMID: 7626127]

Interaction Information:

Comment The levels of KATP-2 mRNA were reduced by 34% in islets from diabetic Zucker diabetic fatty male rats, a model of non-insulin dependent diabetes mellitus, compared to their lean nondiabetic littermates (p < 0.05), suggesting that decreased expression of KATP-2 may contribute to beta-cell dysfunction in this animal model.
Formal Description
Interaction-ID: 51763



affects_activity of

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