General Information:
Id: | 503 (click here to show other Interactions for entry) |
Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
Mus musculus | |
article | |
Reference: | Dzamko N et al.(2008) AMPK-independent pathways regulate skeletal muscle fatty acid oxidation J. Physiol. (Lond.) 586: 5819-5831 [PMID: 18845612] |
Interaction Information:
Comment | Muscle contractions performed ex vivo, in situ or during treadmill exercise activate an alternative kinase capable of phosphorylating ACC2 Ser-221 and stimulating fatty acid oxidation in the absence of increases in AMPK activity. In summary the results demonstrate that AMPK is not essential for the regulation of fatty acid oxidation by AICAR or muscle contraction. |
Formal Description Interaction-ID: 46070 |
process increases_activity of process |