General Information:

Id: 503 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
article
Reference: Dzamko N et al.(2008) AMPK-independent pathways regulate skeletal muscle fatty acid oxidation J. Physiol. (Lond.) 586: 5819-5831 [PMID: 18845612]

Interaction Information:

Comment AICAR stimulated fatty acid oxidation in both wild-type and AMPK KD extensor digitorum longus (EDL) muscle, but not soleus (SOL) muscle.
Formal Description
Interaction-ID: 2491

drug/chemical compound

AICAR

NOT increases_activity of

in skeletal muscle (SOL); in wild-type and AMPK KD mice
Drugbank entries Show/Hide entries for AICAR