General Information:

Id: 4
Diseases: Amyotrophic lateral sclerosis
Cancer
Homo sapiens
BTO:0001819 stria vascularis
article
Reference: Catalano A et al.(2009) The plexin-A1 receptor activates vascular endothelial growth factor-receptor 2 and nuclear factor-kappaB to mediate survival and anchorage-independent growth of malignant mesothelioma cells. Cancer Res. 69: 1485-1493 [PMID: 19176370]

Interaction Information:

Comment Plexin A1 overexpression inhibits apoptosis in met-5a cells (non-malignant transformed human pleural mesothelial cells) exposed to Sema6D plus NP-1 siRNA.
Formal Description
Interaction-ID: 3

gene/protein

PLXNA1

decreases_activity of

if levels of Sema6D and Nrp1 are decreased.