General Information:

Id: 4,986 (click here to show other Interactions for entry)
Diseases: Atherosclerosis
Cardiovascular disease
Homo sapiens
BTO:0004432 HCAEC cell (human coronary artery endothelial cell)
article
Reference: [PMID: 12130721]

Interaction Information:

Comment Ox-LDL increased the expression of LOX-1 mRNA and protein. Pretreatment of HCAECs with simvastatin or atorvastatin decreased ox-LDL-induced up-regulation of LOX-1.
Formal Description
Interaction-ID: 49264

drug/chemical compound

Atorvastatin

decreases_expression of

gene/protein

OLR1

Drugbank entries Show/Hide entries for Atorvastatin
Comment Ox-LDL increased the expression of LOX-1 mRNA and protein. Pretreatment of HCAECs with simvastatin or atorvastatin decreased ox-LDL-induced up-regulation of LOX-1.
Formal Description
Interaction-ID: 49265

drug/chemical compound

Atorvastatin

decreases_quantity of

gene/protein

OLR1

Drugbank entries Show/Hide entries for Atorvastatin