General Information:

Id: 495 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Homo sapiens
BTO:0000567 HeLa cell; BTO:0001009 PC-12 cell
article
Reference: Pridgeon JW et al.(2007) PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1. PLoS Biol. 5: E172 [PMID: 17579517]

Interaction Information:

Comment Treatment of cells with H(2)O(2) induced cytochrome c release from mitochondria to the cytosol a crucial step in the mitochondrial apoptotic cascade.
Formal Description
Interaction-ID: 2383

drug/chemical compound

H2O2

increases_transport of

gene/protein

CYCS

into cytoplasm
Drugbank entries Show/Hide entries for CYCS