General Information:

Id: 4,938 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mus musculus
THY-Tau22 transgenic mouse
Reference: Laurent C et al.(2014) Beneficial effects of caffeine in a transgenic model of Alzheimers disease-like tau pathology Neurobiol. Aging 35: 2079-2090 [PMID: 24780254]

Interaction Information:

Comment Chronic caffeine intake prevents from the development of spatial memory deficits in THY-Tau22 transgenic mice. Improved memory was associated with reduced hippocampal Tau phosphorylation and proteolytic fragments.
Formal Description
Interaction-ID: 48821

drug/chemical compound


decreases_quantity of

protein modification


in hippocampus
Drugbank entries Show/Hide entries for Caffeine