General Information:

Id: 4,904 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Reference: Tornio A et al.(2012) Drug interactions with oral antidiabetic agents: pharmacokinetic mechanisms and clinical implications Trends Pharmacol. Sci. 33: 312-322 [PMID: 22475684]

Interaction Information:

Comment Thiazolidinediones bind to peroxisome proliferator activated receptor-gamma (PPAR-gamma), which results in a slow rise in insulin sensitivity in hepatic, fat and skeletal muscle cells.
Formal Description
Interaction-ID: 48549

drug/chemical compound


increases_activity of

in liver, in adipose tissue, in skeletal muscle