CIDeRGeneral Information:
| Id: | 488 (click here to show other Interactions for entry) |
| Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
| Rattus norvegicus | |
| male | |
| article | |
| Reference: | Ye JM et al.(2002) Prior thiazolidinedione treatment preserves insulin sensitivity in normal rats during acute fatty acid elevation: role of the liver. Endocrinology 143: 4527-4535 [PMID: 12446579] |
Interaction Information:
| Comment | Pioglitazone treatment reduced plasma levels of triglycerides, FFAs, leptin, and insulin by 23%, 21%, 44%, and 29%, respectively, but did not alter glucose concentration. There was a slight (17%) increase in muscle triglyceride content, whereas no differences were found in glycogen and other lipid metabolites in muscle or liver among the groups. |
|
Formal Description Interaction-ID: 2317 |
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| Drugbank entries | Show/Hide entries for Pioglitazone |