General Information:

Id: 4,792 (click here to show other Interactions for entry)
Diseases: Neurological
Obesity - [OMIM]
Homo sapiens
article
Reference: Carpenter CL et al.(2013) Association of dopamine D2 receptor and leptin receptor genes with clinically severe obesity Obesity (Silver Spring) 21: E467-E473 [PMID: 23670889]

Interaction Information:

Comment A significant interaction (P0.04) between DRD2 and LEPR, and a marginally significant interaction (P0.06) between DRD2 and OPRM1 was observed. Genes associated with addictive behavior and appetite control may therefore, in combination, markedly influence development of clinically severe obesity.
Formal Description
Interaction-ID: 47409

gene/protein

DRD2

interacts (colocalizes) with

gene/protein

LEPR

a significant interaction (P0.04)
Drugbank entries Show/Hide entries for DRD2