General Information:

Id: 475 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Homo sapiens
BTO:0000138 midbrain; BTO:0000793 SH-SY5Y cell
article
Reference: Zhu JH et al.(2007) Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death Am. J. Pathol. 170: 75-86 [PMID: 17200184]

Interaction Information:

Comment MPP+-treatment elicit significantly increased levels of the membrane-bound LC3 form. LC3 conjugation to the autophagic vesicle membrane is required for initiation of autophagy.
Formal Description
Interaction-ID: 2208

gene/protein

MAP1LC3A

affects_activity of

process

autophagy