General Information:

Id: 474 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1G93A transgenic mouse, transfected with human SOD1G93A
BTO:0001279 spinal cord
Reference: Fornai F et al.(2008) Lithium delays progression of amyotrophic lateral sclerosis Proc. Natl. Acad. Sci. U.S.A. 105: 2052-2057 [PMID: 18250315]

Interaction Information:

Comment Induction of autophagy by lithium was matched by increased expression of PTEN (the phosphatase acting on PIP3) and a marked reduction in the SER473 phosphorylation of Akt.
Formal Description
Interaction-ID: 2233

drug/chemical compound


increases_activity of



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