General Information:

Id: 474 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1G93A transgenic mouse, transfected with human SOD1G93A
BTO:0001279 spinal cord
article
Reference: Fornai F et al.(2008) Lithium delays progression of amyotrophic lateral sclerosis Proc. Natl. Acad. Sci. U.S.A. 105: 2052-2057 [PMID: 18250315]

Interaction Information:

Comment Lithium administration in G93A mice reduced ubiquitin, and SOD1 aggregates in motor neurons. SOD1 accumulation was markedly cleared.
Formal Description
Interaction-ID: 2209

drug/chemical compound

Lithium

decreases_quantity of

phenotype

SOD1 protein aggregates

in G93A mutant mice, counted in lamina VII
Drugbank entries Show/Hide entries for Lithium