General Information:

Id: 474 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1G93A transgenic mouse, transfected with human SOD1G93A
BTO:0001279 spinal cord
article
Reference: Fornai F et al.(2008) Lithium delays progression of amyotrophic lateral sclerosis Proc. Natl. Acad. Sci. U.S.A. 105: 2052-2057 [PMID: 18250315]

Interaction Information:

Comment Neurons within lamina VII of G93A mice were severely decreased. Lamina VII contains a larger number of interneurons, defined as Renshaw cells. Lithium administration in G93A mice increased the number of neurons, counted in lamina VII.
Formal Description
Interaction-ID: 2204

drug/chemical compound

Lithium

increases_quantity of

tissue/cell line

interneuron

in G93A mutant mice
Drugbank entries Show/Hide entries for Lithium