General Information:

Id: 46 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type I - [OMIM]
Rattus norvegicus
BTO:0000991 pancreatic islet
article
Reference: Manna P et al.(2009) Protective role of arjunolic acid in response to streptozotocin-induced type-I diabetes via the mitochondrial dependent and independent pathways. Toxicology 257: 53-63 [PMID: 19133311]

Interaction Information:

Comment STZ (Streptozotocin) intoxication increased the levels of serum TNF-alpha and NO.
Formal Description
Interaction-ID: 128

drug/chemical compound

Streptozocin

increases_quantity of

drug/chemical compound

NO

in serum; under hyperglycemic condition
Drugbank entries Show/Hide entries for Streptozocin
Comment The addition of arjunolic acid (AA) to STZ treated rats could inhibit or reduce the serum glucose accumulation and decreased the serum NO and TNF-alpha levels.
Formal Description
Interaction-ID: 132

drug/chemical compound

Arjunolic acid

decreases_quantity of

drug/chemical compound

NO

in serum; in STZ treated rats