General Information:

Id: 468 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Rattus norvegicus
male
article
Reference: Cleasby ME et al.(2004) Metformin prevents the development of acute lipid-induced insulin resistance in the rat through altered hepatic signaling mechanisms. Diabetes 53: 3258-3266 [PMID: 15561958]

Interaction Information:

Comment Metformin did not alter the mRNA expression of the gluconeogenetic enzymes fructose 1,6-bisphosphatase FBP and phosphoenolpyruvate carboxykinase PEPCK after lipid infusion.
Formal Description
Interaction-ID: 2190

gene/protein

PCK1

affects_activity of

process

gluconeogenesis

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