General Information:
Id: | 459 (click here to show other Interactions for entry) |
Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance Peutz-Jeghers syndrome - [OMIM] |
Mus musculus | |
male | |
adenovirus-mediated deletion of LKB1 in liver | |
article | |
Reference: | Shaw RJ et al.(2005) The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science 310: 1642-1646 [PMID: 16308421] |
Interaction Information:
Comment | TORC2 is deregulated in LKB1-deficient livers and drives gluconeogenesis. |
Formal Description Interaction-ID: 12749 |
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