General Information:

Id: 459 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Peutz-Jeghers syndrome - [OMIM]
Mus musculus
male
adenovirus-mediated deletion of LKB1 in liver
article
Reference: Shaw RJ et al.(2005) The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science 310: 1642-1646 [PMID: 16308421]

Interaction Information:

Comment TORC2 is deregulated in LKB1-deficient livers and drives gluconeogenesis.
Formal Description
Interaction-ID: 12749

gene/protein

CRTC2

affects_activity of

process

gluconeogenesis