General Information:

Id: 4,589 (click here to show other Interactions for entry)
Diseases: Atherosclerosis
Cardiovascular disease
Homo sapiens
BTO:0000876 monocytes, activated by phorbol myristyl acetate (PMA)
article/cited
Reference: Jiang C et al.(1998) PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines Nature 391: 82-86 [PMID: 9422509]

Interaction Information:

Comment Indomethacin, ibuprofen and fenoprofen inhibit phorbol myristyl acetate-induced cytokine (TNF-alpha) synthesis in monocytes.
Formal Description
Interaction-ID: 45672

drug/chemical compound

Ibuprofen

decreases_quantity of

gene/protein

TNF

if cytokine production has been induced by PMA
Drugbank entries Show/Hide entries for Ibuprofen or TNF