General Information:

Id: 457 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mammalia
review
Reference: de la Monte SM(2009) Insulin resistance and Alzheimers disease BMB Rep 42: 475-481 [PMID: 19712582]

Interaction Information:

Comment In Alzheimer disease increased levels of Abeta are associated with reduced levels of CNS insulin and IGF-1.
Formal Description
Interaction-ID: 2091

gene/protein

Amyloid beta peptide

affects_quantity of

complex/PPI

Insulin

in CNS; if levels of APP / Amyloid beta peptide in AD are increased then level of insulin is reduced