General Information:

Id: 4,570 (click here to show other Interactions for entry)
Diseases: Obesity - [OMIM]
Mus musculus
article
Reference: Barthel A et al.(1998) Protein kinase C modulates the insulin-stimulated increase in Akt1 and Akt3 activity in 3T3-L1 adipocytes Biochem. Biophys. Res. Commun. 243: 509-513 [PMID: 9480839]

Interaction Information:

Comment Both 3T3-L1 fibroblasts and adipocytes expressed Akt3 mRNA. The insulin stimulates the enzymatic activity of Akt1 and Akt3 15- and 7-fold, respectively.
Formal Description
Interaction-ID: 49191

complex/PPI

Insulin

increases_activity of

gene/protein

AKT3

in 3T3-L1 fibroblasts and adipocytes