General Information:

Id: 4,563
Diseases: Metabolic
Mammalia
review
Reference: MacDonald BT et al.(2009) Wnt/beta-catenin signaling: components, mechanisms, and diseases Dev. Cell 17: 9-26 [PMID: 19619488]

Interaction Information:

Comment The signaling by the Wnt family of secreted glycolipoproteins via the transcription co-activator beta-catenin controls embryonic development and adult homeostasis. Cytosolic beta-catenin phosphorylation / degradation and its regulation by Wnt are the essence of Wnt signaling.
Formal Description
Interaction-ID: 45524

gene/protein

CTNNB1

increases_activity of

process

canonical Wnt signaling pathway

Drugbank entries Show/Hide entries for CTNNB1
Comment The signaling by the Wnt family of secreted glycolipoproteins via the transcription co-activator beta-catenin controls embryonic development and adult homeostasis. Cytosolic beta-catenin phosphorylation / degradation and its regulation by Wnt are the essence of Wnt signaling.
Formal Description
Interaction-ID: 53316

process

canonical Wnt signaling pathway

increases_activity of

process

embryo development