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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	453 (click here to show other Interactions for entry)
Diseases:	Neurological
Organism:	Mammalia
Publication type:	article
Reference:	Alegre-Abarrategui J and Wade-Martins R(2009) Parkinson disease, LRRK2 and the endocytic-autophagic pathway. Autophagy 5: 1208-1210 [PMID: 19770575]

Interaction Information:

Comment	Expression of the R1441C mutant form of LRRK2 induces a cellular phenotype of impaired autophagic balance.
Formal Description Interaction-ID: 2009	gene/protein mutant LRRK2-p.R1441C decreases_activity of process autophagy

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