General Information:

Id: 448 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Drosophila melanogaster
BTO:0000142 brain
article
Reference: Imai Y et al.(2008) Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila EMBO J. 27: 2432-2443 [PMID: 18701920]

Interaction Information:

Comment Flies expressing LRRK-mutants showed significantly higher sensitivity to exogenous ROS inducers paraquat and H(2)O(2).
Formal Description
Interaction-ID: 3813

gene/protein mutant

LRRK2-mut

increases_activity of

drug/chemical compound

H2O2