General Information:

Id: 4,335 (click here to show other Interactions for entry)
Diseases: Metabolic
Rattus norvegicus
BTO:0004318 WB-F344 cell
article
Reference: Prochazkova J et al.(2011) The interplay of the aryl hydrocarbon receptor and beta-catenin alters both AhR-dependent transcription and Wnt/beta-catenin signaling in liver progenitors Toxicol. Sci. 122: 349-360 [PMID: 21602191]

Interaction Information:

Comment Observed was an increased accumulation of downshifted/dephosphorylated Dvl2 and 3 forms, as early as 8 h after TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) addition, suggesting that, apart from beta-catenin downregulation, TCDD inhibits further proximate Wnt signaling events.
Formal Description
Interaction-ID: 44472

drug/chemical compound

2,3,7,8-Tetrachlorodibenzodioxin

decreases_activity of