General Information:

Id: 4,335 (click here to show other Interactions for entry)
Diseases: Metabolic
Rattus norvegicus
BTO:0004318 WB-F344 cell
article
Reference: Prochazkova J et al.(2011) The interplay of the aryl hydrocarbon receptor and beta-catenin alters both AhR-dependent transcription and Wnt/beta-catenin signaling in liver progenitors Toxicol. Sci. 122: 349-360 [PMID: 21602191]

Interaction Information:

Comment Persistent AhR activation reduces mRNA levels of Wnt/ beta-Catenin target genes, disrupts cytokeratin expression pattern, and downregulates expression of Kitl and Ncam1.
Formal Description
Interaction-ID: 44439

gene/protein

AHR

decreases_activity of

process

canonical Wnt signaling pathway

by reducing mRNA levels of Wnt/beta-Catenin target genes and disrupting cytokeratin expression pattern
Drugbank entries Show/Hide entries for AHR