CIDeRGeneral Information:
| Id: | 4,335 (click here to show other Interactions for entry) |
| Diseases: |
Metabolic
|
| Rattus norvegicus | |
| BTO:0004318 WB-F344 cell | |
| article | |
| Reference: | Prochazkova J et al.(2011) The interplay of the aryl hydrocarbon receptor and beta-catenin alters both AhR-dependent transcription and Wnt/beta-catenin signaling in liver progenitors Toxicol. Sci. 122: 349-360 [PMID: 21602191] |
Interaction Information:
| Comment | AhR and Wnt/beta-catenin cooperate in the induction of AhR transcriptional targets, such as Cyp1a1 and Cyp1b1. However, simultaneously, the activation of AhR led to a decrease of dephosphorylated active beta-catenin pool, as well as to hypophosphorylation of Dishevelled, participating in regulation of Wnt signaling. |
|
Formal Description Interaction-ID: 44356 |
process increases_expression of gene/protein |