General Information:

Id: 4,327 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Metabolic
Homo sapiens
article/cited
Reference: Salins P et al.(2007) Lovastatin protects human neurons against Abeta-induced toxicity and causes activation of beta-catenin-TCF/LEF signaling Neurosci. Lett. 412: 211-216 [PMID: 17234346]

Interaction Information:

Comment Statins like lovastatin inhibit 3-hydroxy-3-methylglutaryl-CoA reductase (HMG-CoA), blocking thereby cholesterol biosynthesis.(cited information)
Formal Description
Interaction-ID: 44775

drug/chemical compound

Lovastatin

decreases_activity of

gene/protein

HMGCR

blocking thereby cholesterol biosynthesis
Drugbank entries Show/Hide entries for Lovastatin or HMGCR