CIDeRGeneral Information:
| Id: | 4,327 (click here to show other Interactions for entry) |
| Diseases: |
Alzheimer disease
- [OMIM]
Metabolic |
| Homo sapiens | |
| article/cited | |
| Reference: | Salins P et al.(2007) Lovastatin protects human neurons against Abeta-induced toxicity and causes activation of beta-catenin-TCF/LEF signaling Neurosci. Lett. 412: 211-216 [PMID: 17234346] |
Interaction Information:
| Comment | Statins like lovastatin inhibit 3-hydroxy-3-methylglutaryl-CoA reductase (HMG-CoA), blocking thereby cholesterol biosynthesis.(cited information) |
|
Formal Description Interaction-ID: 44775 |
drug/chemical compound decreases_activity of gene/protein |
| Drugbank entries | Show/Hide entries for Lovastatin or HMGCR |