General Information:

Id: 4,309 (click here to show other Interactions for entry)
Diseases: Metabolic
Homo sapiens
BTO:0001581 embryonic stem cell line H1, H9
article
Reference: Zhou J et al.(2009) mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells Proc. Natl. Acad. Sci. U.S.A. 106: 7840-7845 [PMID: 19416884]

Interaction Information:

Comment The Wnt pathway activity was enhanced by mTOR inhibition. Rapamycin rapidly increased luciferase activity in H9 cells transiently transfected with the Top-flash reporter gene, which assesses Wnt/beta-catenin-mediated transcriptional activation.
Formal Description
Interaction-ID: 44903

gene/protein

MTOR

decreases_activity of

in H9 cells
Drugbank entries Show/Hide entries for MTOR